CLINICOPATHOLOGICAL PROFILE OF ANEMIA AMONG ADULT PATIENTS ATTENDING A TERTIARY CARE CENTER
Abstract
Anemia is a common hematological condition with diverse nutritional, inflammatory, renal, and chronic disease-related causes. Complete blood count parameters are useful for initial anemia screening, severity assessment, and red cell indexbased classification. To assess the clinicopathological profile o anemia among adult patients using an open-access complete blood count dataset. This secondary data analysis used the Complete Blood Count Anemia Diagnosis dataset. Adult patient records aged 18 years and above were included after data cleaning. Variables analyzed included age, sex, hemoglobin, red blood cell count, packed cell volume, mean corpuscular volume, mean corpuscular hemoglobin, mean
corpuscular hemoglobin concentration, red cell distribution width, total leukocyte count, and platelet count. Anemia was classified according to hemoglobin-based severity and red cell index-based morphology. Descriptive statistics, chi-square test, Kruskal-Wallis test, and correlation analysis were applied. A total of 338 adult records were analyzed. Anemia was present in 196 patients (57.99%). Mild anemia was observed in 93 patients (27.51%), moderate anemia in 88 patients (26.04%), and severe anemia in 15 patients (4.44%). Normocytic morphology was predominant, seen in 264 patients (78.11%), followed by microcytic and macrocytic patterns. Hemoglobin showed strong positive correlations with packed cell volume and red blood cell count, while red cell distribution width showed a negative correlation with hemoglobin. CBC parameters provide useful preliminary information for anemia severity and morphological classification. However, etiological confirmation requires clinical evaluation and biochemical investigations.
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